Card

Rest in Peace

Mana cost {1}{W}

When this enchantment enters, exile all graveyards. If a card or token would be put into a graveyard from anywhere, exile it instead.

Part of 43 known combos, 3 of them two-card. 3 official rulings.

Bracket

B1 Exhibition — Not in the same deck as its two-card combo partners: Helm of Obedience, Energy Field, Web of Inertia
B2 Core — Not in the same deck as its two-card combo partners: Helm of Obedience, Energy Field, Web of Inertia
B3 Upgraded — Not in the same deck as its early two-card combo partners: Helm of Obedience, Energy Field, Web of Inertia
B4 Optimized — allowed: No restriction beyond the banned list
B5 cEDH — allowed: No restriction beyond the banned list

Two-card combo with Helm of Obedience, Energy Field, Web of Inertia (early with Helm of Obedience, Energy Field, Web of Inertia)

Bracket: Lotus Vault analysis, with Commander Spellbook flags

43 known combos, 3 of them two-card.

Helm of Obedience + Rest in Peace
Produces: Exile target opponent's library
View on Commander Spellbook
Energy Field + Rest in Peace
Produces: Prevent all damage that would be dealt to you by sources you don't control, Lock
View on Commander Spellbook
Web of Inertia + Rest in Peace
Produces: You can't be attacked, Lock
View on Commander Spellbook

2018-03-16 · Wizards of the Coast
While Rest in Peace is on the battlefield, abilities that trigger whenever a creature dies won't trigger because cards and tokens are never put into a player's graveyard.
2018-03-16 · Wizards of the Coast
If a card is discarded while Rest in Peace is on the battlefield, abilities that function when a card is discarded (such as madness) still work, even though that card never reaches a graveyard. In addition, spells or abilities that check the characteristics of a discarded card (such as Chandra Ablaze's first ability) can find that card in exile.
2018-03-16 · Wizards of the Coast
If Rest in Peace is destroyed by a spell, Rest in Peace will be exiled and then the spell will be put into its owner's graveyard.

Rulings: Scryfall · Wizards of the Coast