Card

Nevinyrral's Disk

Mana cost {4}

This artifact enters tapped. {1}, {T}: Destroy all artifacts, creatures, and enchantments.

Part of 15 known combos, 3 of them two-card. 1 official ruling.

Bracket

B1 Exhibition — Not in the same deck as its two-card combo partners: Avacyn, Angel of Hope, Biorhythm, Guardian Beast
B2 Core — Not in the same deck as its two-card combo partners: Avacyn, Angel of Hope, Biorhythm, Guardian Beast
B3 Upgraded — allowed: Its two-card combos are not early, which Bracket 3 allows
B4 Optimized — allowed: No restriction beyond the banned list
B5 cEDH — allowed: No restriction beyond the banned list

Two-card combo with Avacyn, Angel of Hope, Biorhythm, Guardian Beast (none of them early)

Bracket: Lotus Vault analysis, with Commander Spellbook flags

15 known combos, 3 of them two-card.

Avacyn, Angel of Hope + Nevinyrral's Disk
Produces: Destroy all creatures, artifacts, and enchantments opponents control on each of your turns
View on Commander Spellbook
Nevinyrral's Disk + Darksteel Forge + Mycosynth Lattice + Unwinding Clock
Produces: Destroy all permanents opponents control each turn, Lock, Mass Land Denial
View on Commander Spellbook
Mairsil, the Pretender + Aetherling + Anger + Nevinyrral's Disk
Produces: Destroy all creatures, artifacts, and enchantments on each player's turn, Lock
View on Commander Spellbook

2020-11-10 · Wizards of the Coast
You don't sacrifice Nevinyrral's Disk to activate its ability. It's destroyed as part of the ability's resolution if it's still on the battlefield. If an effect gives Nevinyrral's Disk indestructible or regenerates it, it stays on the battlefield.

Rulings: Scryfall · Wizards of the Coast